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See table 'Overall remarks' below for full discussion Other kinetic parameters: None. Details on results: The test material was demonstrated to undergo hydrolysis, evident by the formation of orthophosphate, and also by assessment of individual components.
2020 06 23 ICS 1 Session 2 Example 2 Pseudo code, Dry Run, TraceTable
However, it was not possible to obtain a definitive result for hydrolytic stability since the test material is a complex mixture of phosphates and the concentration of any individual component monitored may be influenced by the hydrolysis of larger complex phosphates. Due to the high volume of tables and figures please see Attachments 4 to 6 Validity criteria fulfilled: yes Conclusions: The test material was demonstrated to undergo hydrolysis, evident by the formation of orthophosphate, and also by assessment of individual components.
This study is conducted according to an appropriate guideline and under the conditions of GLP and therefore the study is considered to be acceptable and to adequately satisfy both the guideline requirement and the regulatory requirement as Sample Pseudo Dating Site key study for this endpoint. Conclusion The test material was demonstrated to undergo hydrolysis, evident by the formation of orthophosphate, and also by assessment of individual components.
Description of key information The key study for the endpoint 'hydrolysis as a function of pH' Butler RE, has been selected on the basis that the study is conducted to Caut femei din Sighișoara recommended OECD guideline and under the conditions of GLP and therefore meets the regulatory requirements for this endpoint.
The key study reports that the test material is a complex mixture of different types of phosphate and as such no meaningful data could Sample Pseudo Dating Site produced.
Sample Pseudo Dating Site this reason, although the test material was observed to be hydrolytically unstable, no further testing Tier 2 was performed. It was demonstrated that the more complex phosphates indicated by exhibiting longer retention times present in the test material hydrolysed to simpler phosphate species such as orthophosphate, pyrophosphate and tripolyphosphate, all of which were observed to increase significantly during the test.
Several components of the test material increased in magnitude during the course of the test. This is consistent with the process of the phosphate species in the test material hydrolysing to other species already present in solution. The amount of orthophosphate present in Sample Pseudo Dating Site test material was initially negligible and not reported as a test material component.
During the study the amount of orthophosphate in the sample solutions increased significantly. Orthophosphate is therefore considered to be the ultimate hydrolysis product. This theory is supported by the additional supporting literature.
Key value for chemical safety assessment Additional information Sodium metaphosphate is not considered to be hydrolytically stable, however as the substance, in aqueous solutions, is a complex mixture of phosphate species a half-life was not determined. The ultimate degradation products of sodium metaphosphate are sodium and orthophosphate ions. However sodium metaphosphate was also observed to hydrolyse to other phosphate species such as pyrophosphate, trimetaphosphate and tripolyphosphate.
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All of these species have also been shown to hydrolyse to orthophosphate. Information on Registered Substances comes from registration dossiers which have been assigned a registration number. This information has not been reviewed or verified by the Agency or any other authority.
- Due to volatilisation of the test material during test system preparation, the concentration of the test solutions within each pH gradually decreased, as they were dispensed into their individual test vessels.
- Sodium metaphosphate - Registration Dossier - ECHA
- The adsorption properties of the imprinted polymer were demonstrated by equilibrium rebinding experiments, Pseudo-second-order kinetic model, Sips isotherm and Scatchard analysis.
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